Aldosterone is generally responsible for the renal absorption of Na + and exceretion of K + from the distal part of the distal convoluted tubule and collecting duct and intestinal absorption of Na + in lesser extend. Zona Glomerulosa: is the outermost layer of the cortex specialized in the production and secretion of minerocorticoids and predominantly aldosterone a hormone involved in extracellular fluid volume and osmolality control.The cortical zonae are the zona glomerulosa, fasciculata and reticularis producing and secreting minerocorticoids, glucocorticoids and sex steroids respectively. The adrenal cortex composes the outer layer of the adrenal gland and consists of three sublayers called zonae each of which produces structurally similar and functionally different compounds and hormones. The adrenal gland divides into the adrenal outer cortex and the adrenal inner medulla with the latter being of neuronal embryonic origin. They have many activities due to their dual embryonic origin during development. The adrenal glands or suprarenal glands are small paired organs situated superiorly to the kidneys resembling caps surrounded by dense adipose tissue.
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